OFFICE OF CLINICAL RESEARCH EDUCATION AND COLLABORATION OUTREACH

Bench-to-Bedside and Back Program (BtB)

Project	Institute or institution/Investigators
Use of 5 Fluorouracil (5FU) in Combination with Antiretroviral Drugs as a Salvage Strategy to Overcome Drug Resistance in Heavily Treated HIV-Infected Pediatric Patients	NCI: Wood, Lauren NIAID: Womack, C.
Imaging Probe for the In Vivo Assessment of HIV-1 Dynamics	NIAID: DiMascio, Michelle; Imamichi, Tomozumi; Lane, Cliff CC: Drs. Pandit and Li
Therapeutic Targeting of a Virally Regulated Host Cell Molecule in HIV Infection	NIDCR: Wahl, Sharon; Vazquez, N. CC: Masur, Henry Dartmouth University: Sporn, M.B.
Role of Recombination in HIV-1 Drug Resistance in vitro and in vivo	NCI: Maldarelli, Frank; Palmer, S; Coffin, J NIAID: Polis, N; Michan, J
Treatment of Drug Resistant and Persistent HIV-1 Infection with the Designed Proteins 5-Helix and 5-Helix-PE	NCI: Hamer, Dean NIAID: Kovacs, Joseph
HIV-1 Infections During Vaccine Trials: Identifying New Peptides for the Differential Diagnosis of HIV-1 Infection in the Face of Vaccine-Generated Antibodies	FDA: Goldberg, Hana NIAID: Graham, Barney
Effect on Immune Responses and Sustainability of Viral Suppression in HIV-Infected Children of a Therapeutic Vaccination Strategy with a Multiclade HIV-1 DNA Plasmid Vaccine Prime and a Recombinant Adenovector Boost	NCI: Zeichner, S NIAID: Kroup, Richard

Project	Project
Investigation of Brain and Behavioral Effects of Specific Gene Deleted in 'Williams Syndrome Critical Area' of Chromosome 7q11.23 in Patients and Knockout Mice	NIMH: Berman, Karen; Crawley, Jacqueline NINDS: Koretsky, Alan
Sialic Acid Replacement in Patients with Hereditary Inclusion Body Myopathy (HIBM) Caused by Mutations in the GNE (Sialuria) Gene	NHGRI: Juizing, M. NINDS: Dalakas, Marinos Partners: Krasnewich, D.; Vasconcelos, O.
MRI Detection of the Migration of Feridex -PPL Labeled Cells into the CNS in Multiple Sclerosis Patients	CC: Frank, Joseph; Jordan, Elaine; Leitman, Susan; Read, E. NINDS: McFarland, Henry; Bielekova, Bibi; Duyn, Jeff Partners: Ali, S.; Lewis, B.; Martin, R.; Richert, N.; Anderson, S.; Carter, C.
Dendritic cell vaccination to augment graft-versus-leukemia after allogeneic stem cell transplantation for acute lymphoblastic leukemia (ALL)	NCI: Mackall, Crystal; Fry, Terry; Gress, Ron NHLBI: Barrett, John CC: Kurlander, Roger; Read, E. Partners: Bishop, M.; Carter, C.; Grubbe, M.
Evaluation of HMG-CoA reductase inhibitors in pulmonary sarcoidosis	NHLBI: Manganiello, Vincent; Farber, Joshua NIAID: Park, Matthew
Clonal Insertion Site Analysis in Rhesus Macaques & NIH Patients Transplanted with Retrovirally-Transduced Hematopoietic Progenitor & Stem Cells: Implications for Leukemogenesis	NHLBI: Dunbar, Cynthia; Donahue, Robert NIAID: Malech, Harry NHGRI: Candotti, Fabio; Baxevanis, Andy

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